“But few companies have delved into nucleoside engineering the way Moderna has, or pursued such a broad range of diseases from the start. Beyond its $100-millionper-year platform research, Moderna runs four wholly owned ventures focused on drugs for infectious diseases, rare diseases, immuno-oncology, and personalized cancer vaccines. It has about 430 full-time employees, spilling across three buildings around biotech-dense Kendall Square. Higher-ups are identified by black-and-white headshots hanging at their office doors.”
“If you can hack the rules of mRNA, “essentially the entire kingdom of life is available for you to play with,” says Hoge, a physician by training who left a position as a health care analyst to become Moderna’s president in 2012.“
The vision of an mRNA drug has beguiled scientists for decades. “It’s a huge idea,” says Michael Heartlein, who heads mRNA research at a competing biotech called RaNA Therapeutics just a few blocks away. “Any protein target where you can think of a potential therapeutic, you can approach that with mRNA.” The single-stranded molecule sets up a temporary protein factory outside a cell’s nucleus and attaches to ribosomes. This cellular machinery translates its sequence of four kinds of nucleosides—adenosine, cytidine, uridine, and guanosine—into a protein. Then it degrades within a day.
If you don’t think that all these very rich biotech titans are not consumed with the idea of world domination, you would be very much mistaken. Nearly every, single people who has become a billionaire in biotech also has a massive ‘messiah complex’ in which they rule all people and make them bow to their authority. Moderna is one such company, and having received untold millions from the Bill and Melinda Gates Foundation, actively fantasize about using their new mRNA vaccine technology to ‘hack the kingdom of life’. But beware, there is ‘death in the pot’ for those who have ears to hear and eyes with which to see.
Photo: thanks to Pixabay.com